D49B0739

‘Darwinian’ test uncovers an antidepressant’s hidden toxicity

Because of undetected toxicity problems, about a third of prescription drugs approved in the U.S. are withdrawn from the market or require added warning labels limiting their use. An exceptionally sensitive toxicity test invented at the University of Utah could make it possible to uncover more of these dangerous side effects early in pharmaceutical development so that fewer patients are given unsafe drugs. Read More

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Past Global Warming Similar to Today’s

The rate at which carbon emissions warmed Earth’s climate almost 56 million years ago resembles modern, human-caused global warming much more than previously believed, but involved two pulses of carbon to the atmosphere, University of Utah researchers and their colleagues found. Read More

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Ebola Virus May Replicate in an Exotic Way

University of Utah researchers ran biochemical analysis and computer simulations of a livestock virus to discover a likely and exotic mechanism to explain the replication of related viruses such as Ebola, measles and rabies. The mechanism may be a possible target for new treatments within a decade. Read More

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Human DNA Shows Traces of 40 Million-Year Battle For Survival Between Primate and Pathogen

Dec. 11, 2014 – Examination of DNA from 21 primate species – from squirrel monkeys to humans – exposes an evolutionary war against infectious bacteria over iron that circulates in the bloodstream. Supported by experimental evidence, these findings, published in Science on Dec. 12, demonstrate the vital importance of an underappreciated defense mechanism, nutritional immunity. Read More

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Despite National Trend, Salt Lake Valley Residents Prefer Single-Family Neighborhoods

As smart growth becomes a popular urban housing trend in the U.S., a new study from the University of Utah found that Salt Lake valley residents want smarter growth but still cling to the American Dream of a single family house in the suburbs. The study was published Dec. 8 by the journal Housing Policy Debate. Read More