A small chemical change — shifting the position of two hydrogen atoms — makes the difference between mice that are healthy and mice with insulin resistance and fatty liver, major risk factors for diabetes and heart disease. Making the change prevented the onset of these symptoms in mice fed a high-fat diet and reversed prediabetes […]
Few treatments exist for neurodegenerative diseases that progressively rob a person’s ability to move and think, yet the results of a new study are opening additional approaches for exploration. Scientists at University of Utah Health report for the first time that a protein, called Staufen1, accumulates in cells of patients suffering from degenerative ataxia or […]
When grandpa nudges the settings on the thermostat, there’s likely a good reason. Humans, like other animals, become more sensitive to cold with age. Now, scientists from University of Utah Health report that delivering a single dose of a nutritional supplement called L-carnitine to older mice restores a youthful ability to adapt to the cold. After treatment, […]